How many diamox

Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Chlorpheniramine; Hydrocodone; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine.

Chlorpheniramine; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Chlorpropamide: Minor Carbonic anhydrase inhibitors may alter blood sugar. Ciprofloxacin: Minor A large proportion of ciprofloxacin is normally excreted unchanged in the urine. If urinary alkalinizing agents such as carbonic anhydrase inhibitors are used concomitantly, the solubility of ciprofloxacin can be decreased because of alkaline urine.

Patients should be monitored for crystalluria and nephrotoxicity. Cisapride: Major Cisapride should be used with great caution in patients receiving potassium-wasting diuretic therapies, including carbonic anhydrase inhibitors.

Drugs that are associated with depletion of electrolytes may cause cisapride-induced cardiac arrhythmias. Serum electrolytes potassium, calcium, and magnesium and creatinine should be assessed prior to administration of cisapride and whenever conditions develop that may affect electrolyte imbalance or renal function. Cisapride is contraindicated for use in patients with known serum electrolyte imbalances; cisapride should be discontinued if such imbalances occur.

Cisatracurium: Moderate Nondepolarizing neuromuscular blockers when combined with carbonic anhydrase inhibitors may lead to prolonged respiratory depression.

Citalopram: Moderate Caution is advisable during concurrent use of citalopram and acetazolamide as electrolyte imbalance caused by diuretics may increase the risk of QT prolongation with citalopram.

Clozapine: Moderate Caution is advisable during concurrent use of clozapine and acetazolamide as electrolyte imbalance caused by diuretics may increase the risk of QT prolongation with clozapine. Corticosteroids: Moderate Corticosteroids may increase the risk of hypokalemia if used concurrently with acetazolamide. Hypokalemia may be especially severe with prolonged use of corticotropin, ACTH. Cyclosporine: Minor Acetazolamide may increase serum cyclosporine concentrations.

If cyclosporine and acetazolamide are to be coadministered, monitor the patient for cyclosporine toxicity. Dapagliflozin; Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Dapagliflozin; Saxagliptin: Minor Carbonic anhydrase inhibitors may alter blood sugar. Desloratadine; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine.

Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Dextroamphetamine: Moderate Urinary alkalinizers, such as acetazolamide, result in decreased renal excretion of amphetamines. Dextromethorphan; Guaifenesin; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Dextromethorphan; Quinidine: Major Acetazolamide can decrease excretion of quinidine because carbonic anhydrase inhibitors increase the alkalinity of the urine, thereby increasing the amount of nonionized drug available for renal tubular reabsorption.

The effects of quinidine can be prolonged or enhanced. Dichlorphenamide: Major Use dichlorphenamide and acetazolamide, another carbonic anhydrase inhibitor, together with caution as both drugs can cause metabolic acidosis. Concurrent use may increase the severity of metabolic acidosis. Measure sodium bicarbonate concentrations at baseline and periodically during dichlorphenamide treatment. If metabolic acidosis occurs or persists, consider reducing the dose or discontinuing dichlorphenamide therapy.

Diflunisal: Moderate The concomitant use of diflunisal and acetazolamide has resulted in a significant decrease in intraocular pressure due to increased concentrations of acetazolamide. If diflunisal and acetazolamide are used concurrently, monitor the patient for signs and symptoms of toxicity; reduced drug dosages may be needed. Digoxin: Moderate Carbonic anhydrase inhibitors can result in hypokalemia. Patients receiving these drugs concurrently with cardiac glycosides are at an increased risk for digitalis toxicity if hypokalemia develops during treatment.

Ventricular irritability may occur. Monitor for hypokalemia and supplement with potassium if needed. Dihydrocodeine; Guaifenesin; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Donepezil; Memantine: Moderate Systemic carbonic anhydrous inhibitors have the potential to increase urine pH, and potentially reduce the renal clearance of memantine.

Increases in urinary pH may decrease elimination of memantine, resulting in drug accumulation and potential toxicity. Doxacurium: Moderate Nondepolarizing neuromuscular blockers when combined with carbonic anhydrase inhibitors may lead to prolonged respiratory depression. Droperidol: Moderate Caution is advised when using droperidol in combination with other agents that may lead to electrolyte abnormalities, such as carbonic anhydrase inhibitors, especially hypokalemia or hypomagnesemia, as such abnormalities may increase the risk for QT prolongation or cardiac arrhythmias.

Empagliflozin; Linagliptin: Minor Carbonic anhydrase inhibitors may alter blood sugar. Empagliflozin; Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Ephedrine: Major Acetazolamide or methazolamide can decrease excretion and enhance the effects of ephedrine.

Carbonic anhydrase inhibitors increase the alkalinity of the urine, thereby increasing the amount of nonionized ephedrine available for renal tubular reabsorption. If concurrent use cannot be avoided, monitor for the appearance of ephedrine-related toxicity.

Epoprostenol: Moderate Further reductions in blood pressure may occur when epoprostenol is administered with other antihypertensive agents. Ertugliflozin; Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis.

Ertugliflozin; Sitagliptin: Minor Carbonic anhydrase inhibitors may alter blood sugar. Ethacrynic Acid: Moderate Carbonic anhydrase inhibitors promote electrolyte excretion including hydrogen ions, sodium, and potassium.

Ethotoin: Minor Acetazolamide or methazolamide can induce osteomalacia in patients being concomitantly treated with hydantoin anticonvulsants. The carbonic anhydrase inhibitors increase the rate of urinary calcium excretion; phenytoin increases the metabolism of the D vitamins.

When combined, the effects on bone catabolism can be additive. Fexofenadine; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine.

Flecainide: Moderate Carbonic anhydrase inhibitors can decrease the urinary excretion and enhance the clinical effects of flecainide. Carbonic anhydrase inhibitors increase the alkalinity of the urine, thereby increasing the amount of nonionized drug available for renal tubular reabsorption into the systemic circulation. Fosphenytoin: Minor Acetazolamide or methazolamide can induce osteomalacia in patients being concomitantly treated with hydantoin anticonvulsants.

Furosemide: Moderate Carbonic anhydrase inhibitors promote electrolyte excretion including hydrogen ions, sodium, and potassium. Gallium Ga 68 Dotatate: Moderate Carbonic anhydrase inhibitors promote electrolyte excretion including hydrogen ions, sodium, and potassium.

Glimepiride: Minor Carbonic anhydrase inhibitors may alter blood sugar. Glimepiride; Pioglitazone: Minor Carbonic anhydrase inhibitors may alter blood sugar. Glimepiride; Rosiglitazone: Minor Carbonic anhydrase inhibitors may alter blood sugar. Glipizide: Minor Carbonic anhydrase inhibitors may alter blood sugar. Glipizide; Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis.

Glyburide: Minor Carbonic anhydrase inhibitors may alter blood sugar. Glyburide; Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Guaifenesin; Hydrocodone; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine.

Guaifenesin; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Electrolyte imbalances may occur while on these diuretics, which may in turn predispose patients to the cardiac effects of halofantrine. Haloperidol: Moderate Caution is advisable during concurrent use of haloperidol and acetazolamide as electrolyte imbalance caused by diuretics may increase the risk of QT prolongation with haloperidol.

Hydantoins: Minor Acetazolamide or methazolamide can induce osteomalacia in patients being concomitantly treated with hydantoin anticonvulsants.

Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Hydrocodone; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Hydroxychloroquine: Moderate Caution is warranted with the coadministration of hydroxychloroquine and antiepileptic drugs, such as acetazolamide.

Hydroxychloroquine can lower the seizure threshold; therefore, the activity of antiepileptic drugs may be impaired with concomitant use. Ibuprofen; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Iloprost: Moderate Further reductions in blood pressure may occur when inhaled iloprost is administered to patients receiving other antihypertensive agents.

Inamrinone: Moderate Hypokalemia may occur due to excessive diuresis during inamrinone therapy. Fluid and electrolyte changes and renal function should be carefully monitored during inamrinone therapy.

Incretin Mimetics: Minor Carbonic anhydrase inhibitors may alter blood sugar. Insulins: Minor Carbonic anhydrase inhibitors may alter blood sugar. Kava Kava, Piper methysticum: Major Any substances that act on the CNS, including anticonvulsants, may have a pharmacodynamic interaction with kava kava.

Levalbuterol: Moderate Albuterol may cause additive hypokalemia when coadministered with carbonic anhydrase inhibitors. Levomethadyl: Major Acetazolamide can potentiate hypokalemia. Patients receiving acetazolamide concurrently with levomethadyl are at an increased risk for cardiac toxicity if hypokalemia develops during treatment.

Linagliptin: Minor Carbonic anhydrase inhibitors may alter blood sugar. Linagliptin; Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Lisdexamfetamine: Moderate Urinary alkalinizers, such as acetazolamide and methazolamide, result in decreased renal excretion of amphetamines. Alkaline urine will significantly increase the half-life of lisdexamfetamine. Lithium: Moderate Carbonic anhydrase inhibitors interfere with lithium reabsorption at the proximal tubule, the primary site of lithium reabsorption.

Thus, lithium serum concentrations are likely to decrease during administration of carbonic anhydrase inhibitors. If carbonic anhydrase inhibitor therapy is needed during lithium administration, monitoring of lithium concentrations is recommended, along with clinical monitoring for evidence of a decrease in lithium efficacy.

Patients should promptly report persistent changes in moods or behaviors. Loop diuretics: Moderate Carbonic anhydrase inhibitors promote electrolyte excretion including hydrogen ions, sodium, and potassium. Loratadine; Pseudoephedrine: Moderate Acetazolamide and methazolamide can decrease excretion and enhance the effects of pseudoephedrine. Magnesium Hydroxide: Moderate Diuretics may interfere with the kidneys ability to regulate magnesium concentrations.

Magnesium Salts: Moderate Diuretics may interfere with the kidneys ability to regulate magnesium concentrations. Minor Diuretics may interfere with the kidneys ability to regulate magnesium concentrations. Mannitol: Moderate Carbonic anhydrase inhibitors promote electrolyte excretion including hydrogen ions, sodium, and potassium. Mefloquine: Moderate Coadministration of mefloquine and anticonvulsants may result in lower than expected anticonvulsant concentrations and loss of seizure control.

Monitoring of the anticonvulsant serum concentration is recommended. Dosage adjustments may be required during and after therapy with mefloquine.

Memantine: Moderate Systemic carbonic anhydrous inhibitors have the potential to increase urine pH, and potentially reduce the renal clearance of memantine. Mephobarbital: Minor Acetazolamide can induce osteomalacia in patients treated chronically with barbiturates. Metformin: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis.

Metformin; Pioglitazone: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Metformin; Repaglinide: Moderate Carbonic anhydrase inhibitors such as acetazolamide frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Minor Acetazolamide has rarely caused hyperglycemia and glycosuria in patients with diabetes mellitus, probably due to drug-induced hypokalemia.

Because of this, a potential pharmacodynamic interaction exists between acetazolamide and repaglinide. Reality : It helps speed up the natural acclimatization process. Only your physician can answer that question. It certainly is not necessary, others simply want to use every tool in the box to help them with the elevation. Untested products spring up from time to time making exaggerated claims.

For minor pain relief on the mountain, ibuprofen is normally recommended as narcotic pain medications can result in slower breathing and can cause problems at altitude. If you are on pain medication for any reason, speak to your doctor. As with most of Africa, malaria is always a concern when traveling through Tanzania. As the mosquitos are generally not found above ft, you are relatively safe whilst on the mountain. Malaria is a parasite transmitted through the bite of the female anopheles mosquito.

It only takes one bite to be infected, and the illness is serious, sometimes fatal. Talk to your doctor about anti-malarial prophylaxis, and which is the most suitable for you and where you are traveling to. Malarone is a popular, but expensive brand, with the fewest reported side-effects. I am 28, male, very near sighted I always have a "normal" eye pressure, ranges from Three years ago Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions.

Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy.

Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions. Acetazolamide helps to reduce increased eye pressure glaucoma.

There are a number of common side-effects, but they are not usually serious. In this article About acetazolamide Before taking acetazolamide How to take acetazolamide Getting the most from your treatment Can acetazolamide cause problems? How to store acetazolamide Important information about all medicines. Acetazolamide for glaucoma Diamox, Eytazox In this article About acetazolamide Before taking acetazolamide How to take acetazolamide Getting the most from your treatment Can acetazolamide cause problems?

Common acetazolamide side-effects What can I do if I experience this? The most common milder side effects with Diamox include:. In addition, many people report an annoying change in their taste sensation. This seems to be especially the case with regard to carbonated beverages; Diamox can make these beverages quite unpleasant to the taste. Some side effects are more difficult to tolerate. If these more troublesome side effects occur, you should report them to your healthcare provider right away.

They may include:. Serious side effects are also possible with Diamox that require immediate medical attention, including:. Allergic reactions to Diamox are relatively uncommon, but they do occur. Symptoms may be relatively mild rash, itching, mouth blisters , or may be a life-threatening emergency anaphylaxis, including severe dizziness, rash, severe shortness of breath, and loss of consciousness.

Any sign of an allergic reaction to any drug should be reported right away to your healthcare provider, and if signs suggesting anaphylaxis occur, should be called immediately.

Sometimes Diamox may cause impaired mental alertness or physical incoordination, so caution should be taken if driving or operating machinery. People with diabetes may see a change in blood glucose control with Diamox, which may cause blood glucose levels to become either lower or higher.

Diamox may worsen chronic liver disease. People with severe chronic lung disease may experience more breathing difficulty while taking Diamox. Diamox can make sunburn more likely. People should avoid prolonged exposure to sunlight while on Diamox, especially if they get sunburned easily.

Many drug interactions have been reported with Diamox, so it is important that your healthcare provider know all the medicines and supplements you may be taking, whether from prescriptions or over the counter. Some of the notable drugs that can negatively interact with Diamox include:. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life.

Medical interventions for primary open angle glaucoma and ocular hypertension. Acetazolamide in the treatment of acute mountain sickness: clinical efficacy and effect on gas exchange. Ann Intern Med ; Fontaine B. Periodic paralysis. Adv Genet ; Williams MA, Malm J. Diagnosis and treatment of idiopathic normal pressure hydrocephalus. Neurology ; Efficacy and tolerability of acetazolamide in migraine prophylaxis: a randomized placebo-controlled trial.

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